South Carolina Physician Collaboration
Find a collaborating physician in South Carolina
GuardianMD matches nurse practitioners and physician assistants with physicians licensed in South Carolina, and supports the agreement and oversight their role requires.
Licensed in South Carolina
Agreements built around state requirements
Get matched
Fast physician matching in South Carolina
South Carolina nurse practitioners must perform medical acts under a written practice agreement with a physician who actively practices in South Carolina and is readily available for consultation. GuardianMD helps eligible South Carolina NPs find a collaborating physician whose clinical experience fits their specialty, patient population, and practice locations. Read South Carolina APRN practice agreement law.
Getting started in South Carolina
Everything your South Carolina practice needs to get started
Getting started in South Carolina involves the practice agreement, consultation and backup arrangements, and your prescribing plans. The agreement is reviewed at least once a year, and changes to your physician or practice location must be reported to the Board of Nursing. Ask about GuardianMD support for onboarding and keeping the agreement current. Read South Carolina Board of Nursing APRN resources.
Who we serve
Collaboration for every practice type in South Carolina
We welcome South Carolina NPs planning a new clinic, replacing a collaborator, or expanding an established practice. Primary care, behavioral health, medical weight management, and other clinical models can be discussed during intake. Eligibility depends on the services, clinician qualifications, physician fit, and setting. Include every proposed practice location and any telehealth component. Support is available to licensed, eligible NPs who meet GuardianMD requirements. Services may be limited or adjusted by jurisdiction and plan.
How it works
From the first call to ongoing support
Tell us about your practice
Share your license type, service lines, and where you plan to operate in South Carolina
Get matched to a physician
We identify a physician licensed in South Carolina whose specialty aligns with the care you deliver.
Review the agreement
Your agreement is built around state requirements and walked through with you before signing.
Stay supported
Coordinated chart reviews, protocol updates, and physician access continue through the platform.
State Resources
Helpful links to South Carolina’s licensing boards
This reference outlines the essential state medical compliance regulations that guide daily clinical practice and patient care. It serves as a quick-reference tool to help maintain the highest standards of legal and professional compliance.
The resources below link to the state’s official licensing boards.
South Carolina Board of Medical Examiners: https://llr.sc.gov/med/
South Carolina Board of Nursing: https://llr.sc.gov/nurse/
South Carolina Board of Pharmacy: https://llr.sc.gov/bop/
Because healthcare regulations are frequently updated, please use this reference as a general guide and always defer to the current mandates of your State Boards of Medicine, Nursing, and Pharmacy.
Common questions
Collaboration in South Carolina
How do I find a collaborating physician in South Carolina?
NPs in South Carolina can find a collaborating physician through a physician collaboration service such as GuardianMD, an employer or health system, or a physician they already know. With GuardianMD, share your specialty, patient population, practice locations, and prescribing plans so we can discuss physician fit. Learn how GuardianMD helps NPs find a collaborating physician.
Do nurse practitioners in South Carolina need a collaborating physician?
Yes. South Carolina NPs must perform medical acts under a written practice agreement with a physician who is readily available for consultation. South Carolina has not adopted full practice authority for NPs. Read South Carolina APRN practice agreement law.
What does a South Carolina practice agreement include?
A South Carolina practice agreement identifies both providers and describes practice locations, consultation and backup arrangements, the conditions and treatments covered, prescribing, and referrals. Read South Carolina APRN practice agreement law.
Does a South Carolina collaborating physician need to be on site?
No. The collaborating physician must be actively practicing in South Carolina and readily available in person or by telecommunications, but does not need to be on site. Read South Carolina APRN practice agreement law.
How often must a South Carolina practice agreement be reviewed?
At least once a year. The agreement must be signed and dated by both providers, and the Board can request a copy at any time. Read South Carolina APRN practice agreement law.
How do South Carolina NPs report physician or location changes?
South Carolina NPs must notify the Board of Nursing within 15 business days when their collaborating physician or practice location changes. Read South Carolina APRN practice agreement law.
How does GuardianMD support NPs in South Carolina?
GuardianMD offers eligible South Carolina NPs physician matching, onboarding support, document organization, and ongoing communication with their collaborating physician through DocTalk, depending on the plan. Collaborating physician fees are included in the monthly plan price. The NP and physician remain responsible for clinical decisions.
Last updated: October 25, 2026