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Missouri Physician Collaboration

Find a collaborating physician in Missouri

GuardianMD matches nurse practitioners and physician assistants with physicians licensed in Missouri, and supports the agreement and oversight their role requires.


Licensed in Missouri

Agreements built around state requirements

Talk with a specialist

Get matched

Fast physician matching in Missouri

Missouri nurse practitioners must practice under a collaborative practice arrangement with a Missouri-licensed physician. GuardianMD helps eligible Missouri NPs find a collaborating physician able to participate in the arrangement, based on patient population, services, prescribing, and practice locations. Read Missouri collaborative practice statute.


Getting started in Missouri

Everything your Missouri practice needs to get started

Getting started in Missouri involves the written arrangement, consultation and referral guidelines, regular chart review, and a plan for physician participation, including an initial period with the physician on site. Ask about GuardianMD support organizing documents and recurring activities. Read Missouri State Board of Registration for the Healing Arts.


Who we serve

Collaboration for every practice type in Missouri

We welcome Missouri NPs launching a clinic, replacing a collaborator, or adding services to an existing practice. Share your primary care, behavioral health, medical weight management, or other clinical focus. Eligibility depends on provider qualifications, the services and locations involved, and available physician participation. Include plans for both in-person and telehealth care. Support is available to licensed, eligible NPs who meet GuardianMD requirements. Services may be limited or adjusted by jurisdiction and plan.

How it works

From the first call to ongoing support

Tell us about your practice

Share your license type, service lines, and where you plan to operate in Missouri

Get matched to a physician

We identify a physician licensed in Missouri whose specialty aligns with the care you deliver.

Review the agreement

Your agreement is built around state requirements and walked through with you before signing.

Stay supported

Coordinated chart reviews, protocol updates, and physician access continue through the platform.

State Resources

Helpful links to Missouri’s licensing boards

This reference outlines the essential state medical compliance regulations that guide daily clinical practice and patient care. It serves as a quick-reference tool to help maintain the highest standards of legal and professional compliance.

The resources below link to the state’s official licensing boards.

Missouri State Board of Registration for the Healing Arts: https://pr.mo.gov/healingarts.asp
Missouri State Board of Nursing: https://pr.mo.gov/nursing.asp
Missouri Board of Pharmacy: https://pr.mo.gov/pharmacists.asp

Because healthcare regulations are frequently updated, please use this reference as a general guide and always defer to the current mandates of your State Boards of Medicine, Nursing, and Pharmacy.


Common questions

Collaboration in Missouri

How do I find a collaborating physician in Missouri?

NPs in Missouri can find a collaborating physician through a physician collaboration service such as GuardianMD, an employer or health system, or a physician they already know. With GuardianMD, share your specialty, patient population, practice locations, and prescribing plans so we can discuss physician fit. Learn how GuardianMD helps NPs find a collaborating physician.

Do nurse practitioners in Missouri need a collaborating physician?

Yes. Missouri NPs must practice under a collaborative practice arrangement with a physician, which can take the form of a written agreement, jointly agreed protocols, or standing orders. Read Missouri collaborative practice statute.

Does a Missouri collaborating physician need to be on site?

At first, yes. Missouri generally requires the collaborating physician to be continuously present during the first month of practice together. After that, the physician must stay available for consultation, and some arrangements also require periodic physician presence. Read Missouri collaborative practice statute.

What chart review does Missouri require?

Missouri requires the collaborating physician to review at least 10% of the APRN’s charts every 14 days, with a higher review rate for charts involving controlled substances. Read Missouri collaborative practice statute.

How many NPs can a Missouri physician collaborate with?

A Missouri physician can collaborate with up to six full-time-equivalent APRNs, physician assistants, and assistant physicians combined. Read Missouri collaborative practice statute.

What can a Missouri collaborative arrangement cover?

A Missouri arrangement can only cover care within both providers’ training and scope, and it must include guidelines for consultation and referral. Read Missouri collaborative practice rules.

How does GuardianMD support NPs in Missouri?

GuardianMD offers eligible Missouri NPs physician matching, onboarding support, document organization, and ongoing communication with their collaborating physician through DocTalk, depending on the plan. Collaborating physician fees are included in the monthly plan price. The NP and physician remain responsible for clinical decisions.

Last updated: October 25, 2026

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