Mississippi Physician Collaboration
Find a collaborating physician in Mississippi
GuardianMD matches nurse practitioners and physician assistants with physicians licensed in Mississippi, and supports the agreement and oversight their role requires.
Licensed in Mississippi
Agreements built around state requirements
Get matched
Fast physician matching in Mississippi
Mississippi nurse practitioners must practice in a collaborative relationship with a Mississippi-licensed physician, and the Board of Nursing must approve the physician, practice site, and agreement before practice begins. GuardianMD helps eligible Mississippi NPs find a collaborating physician based on clinical focus, experience, and practice sites. Read Mississippi Board of Nursing APRN guidance.
Getting started in Mississippi
Everything your Mississippi practice needs to get started
Getting started in Mississippi involves a collaborative agreement for each practice site, a quality assurance plan, and approvals from the Board of Nursing and the Board of Medical Licensure. New APRNs also complete a period of monitored practice, so include that in your plan. Ask about GuardianMD support organizing documentation and communication. Read Mississippi Board of Nursing APRN guidance.
Who we serve
Collaboration for every practice type in Mississippi
We welcome Mississippi NPs preparing to open a clinic, changing physicians, or adding a practice site. Tell us about primary care, behavioral health, medical weight management, or other proposed services. Eligibility depends on your qualifications, experience, clinical scope, practice setting, and physician availability. A new graduate’s onboarding needs may differ from those of an experienced NP. Support is available to licensed, eligible NPs who meet GuardianMD requirements. Services may be limited or adjusted by jurisdiction and plan.
How it works
From the first call to ongoing support
Tell us about your practice
Share your license type, service lines, and where you plan to operate in Mississippi
Get matched to a physician
We identify a physician licensed in Mississippi whose specialty aligns with the care you deliver.
Review the agreement
Your agreement is built around state requirements and walked through with you before signing.
Stay supported
Coordinated chart reviews, protocol updates, and physician access continue through the platform.
State Resources
Helpful links to Mississippi’s licensing boards
This reference outlines the essential state medical compliance regulations that guide daily clinical practice and patient care. It serves as a quick-reference tool to help maintain the highest standards of legal and professional compliance.
The resources below link to the state’s official licensing boards.
Mississippi State Board of Medical Licensure: https://www.msbml.ms.gov/
Mississippi Board of Nursing: https://www.msbn.ms.gov/
Mississippi Board of Pharmacy: https://www.mbp.ms.gov/
Because healthcare regulations are frequently updated, please use this reference as a general guide and always defer to the current mandates of your State Boards of Medicine, Nursing, and Pharmacy.
Common questions
Collaboration in Mississippi
How do I find a collaborating physician in Mississippi?
NPs in Mississippi can find a collaborating physician through a physician collaboration service such as GuardianMD, an employer or health system, or a physician they already know. With GuardianMD, share your specialty, patient population, practice locations, and prescribing plans so we can discuss physician fit. Learn how GuardianMD helps NPs find a collaborating physician.
Do nurse practitioners in Mississippi need a collaborating physician?
Yes. All Mississippi APRNs must practice in a collaborative relationship with a Mississippi-licensed physician. Mississippi does not offer an independent practice option for NPs. Read Mississippi Board of Nursing APRN guidance.
Do new Mississippi NPs have extra requirements?
Yes. New Mississippi APRNs must complete a set number of monitored practice hours with a qualifying provider before practicing on their own at a site. The number of hours depends on prior RN experience. Read Mississippi Board of Nursing APRN guidance.
How does physician oversight work in Mississippi?
In Mississippi, the collaborating physician reviews a monthly sample of the APRN’s charts and meets with the APRN each quarter, in person or by video, as part of a quality improvement program. Read Mississippi Board of Medical Licensure quality improvement rule.
Do Mississippi NPs need an agreement for each practice site?
Yes. Mississippi requires a collaborative agreement on file for each practice site. Share all of your intended locations during intake. Read Mississippi Board of Nursing APRN guidance.
Is there a distance limit for collaboration in Mississippi?
Mississippi requires additional Board approval when an APRN practices more than 75 miles from the collaborating physician, with exceptions for certain primary care practices. Read Mississippi Board of Medical Licensure extended mileage rule.
How does GuardianMD support NPs in Mississippi?
GuardianMD offers eligible Mississippi NPs physician matching, onboarding support, document organization, and ongoing communication with their collaborating physician through DocTalk, depending on the plan. Collaborating physician fees are included in the monthly plan price. The NP and physician remain responsible for clinical decisions.
Last updated: October 25, 2026